Falavigna, Margherita; Klitgaard, Mette; Berthelsen, Ragna; Mullertz, Anette; Flaten, Gøril Eide (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-08)
The aim of this work was to develop a new in vitro lipolysis-permeation model to predict the in vivo absorption of fenofibrate in self-nanoemulsifying drug delivery systems (SNEDDSs). More specifically, the in vitro intestinal lipolysis model was combined with the mucus-PVPA (Phospholipid Vesicle-based Permeation Assay) in vitro permeability model. Biosimilar mucus (BM) was added to the surface of ...